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Research in the laboratory is related to the cellular processes occurring during development of the embryo before implantation, including fertilisation, cell division and cell differentiation. In particular, we are studying the regulation of ion channels during development and whether they are involved in progression of the cell cycle. We have recently demonstrated the presence of a novel cell cycle clock in early mouse embryos that functions independent of the nucleus. We are currently investigating the intracellular signalling pathways involved in regulation of this clock and how it is linked to the nuclear cell cycle. In the laboratory we use techniques such as patch-clamping, molecular biology and methods for studying protein expression.

Personnel:
Dr Margot Day - Head of Laboratory
Charmaine Green – PhD student
Sarah Dalati – PhD student
Salini Sreedharan – MPhil student
Tamara Treleaven – MPhil student
Nicola Pitt - PhD student
Radu Zamfirescu - PhD student
Marisa Perera - Honours student

mouse

Dr Margot Day
Discipline of Physiology and Bosch Institute,

Rm 232, level 2, Medical Foundation Building (K25) University of Sydney 92-94 Parramatta Rd
NSW 2006 AUSTRALIA
Email: margotd@physiol.usyd.edu.au
Phone: +61 2 9036 3312
Fax: +61 2 9036 3316