MEDICAL SCIENCES TALENTED STUDENTS PROGRAM

 

Meddling with Medical Science

Molecular and cellular biology, latest imaging and recording techniques and various non-invasive approaches offer the potential to answer questions in the medical science Disciplines of Anatomy, Histology, Infectious Diseases, Immunology, Physiology, Pharmacology, Neuroscience and Pathology. This TSP program offers students the chance to be a member of one of the research labs in these Disciplines and meet regularly with academics to discuss cutting edge research.

Choosing a Topic and Enrolling:

Second or third year students who wish to participate in this program will need to enrol in a generic 6CP TSP unit of study. You can exchange a 6CP course for 6 TSP credit points.

To enrol please contact one of the co-ordinators of the SMS TSP program:

The co-ordinators can help you to find a project/research area that you are interested in.

See below for a list of topics available this semester. These may be either laboratory based projects or library-based research projects.

Time commitment:

4-5 hrs per week + usual study/research reading commitment in own time

Structure of SMS TSP program:

Fortnightly meeting with fellow TSP students in the SMS Program convened by the co-ordinators. In these sessions we will discuss the expectations of the program and provide tutoring on how to critically review literature, understand biological variation, analyse data, write research reports and give oral presentations. Each student will give short progress talks to the group about their research.

Assessment:

Laboratory Based Projects:

·          Final oral presentation to the School in the last week of semester (10 min talk + 5 min questions) (15%)

Library Based Projects:

Research Projects

Projects are available in the following Disciplines:

Anatomy and Histology

Infectious Diseases and Immunology

Pathology

Pharmacology

Physiology

 

Circulation & respiration

Ghrelin in the brain: role in gastrointestinal and cardiovascular function.

Supervisor: Prof. Roger Dampney, Physiology

The role of the RNA binding protein HuR (an RNA binding protein) in inflammatory pathways underlying cancer and airway remodelling.

Supervisor: Dr Alaina Ammit, Pharmacy, Collaboration with the Discipline of Pharmacology

Role of steroids in airway remodelling (library project)

Supervisor: Dr Brian Oliver, Pharmacology

Developing an in vitro model to simulate the effect of breathing on airway diameter; i.e. marrying motors with airways dissected from pig lung.

Supervisor: Dr Brent McParland, Pharmacology

Effects of respiratory frequency and tidal volume on resting airway caliber

Supervisor: Dr Cheryl Salome, Medicine; collaboration with the Discipline of Pharmacology

Arthrosclerosis/cardiovascular disease

Supervisor: A/Prof. Brett Hambly, Pathology

 

Nervous system, senses & movement

Chemical conversations that underlie the growth and survival of synapses

Supervisor: Dr Bill Phillips, Physiology

Revealing circuits underlying volitional (self-initiated) behaviour

Supervisor: Dr Atomu Sawatari, Physiology

Development of molecular probes for studying diseases of the brain

Supervisor: A/Prof. Michael Kassiou, Medicinal Chemistry/ Pharmacology

Central nervous system stability and degeneration

Supervisor: Prof. Jonathan Stone, Physiology

 

Retinal development & neural circuits 

Lens development & cataract

Supervisor: A/Prof. Frank Lovicu, Anatomy & Histology

Visual perception in natural scenes

Supervisor: Dr Samuel Solomon, Physiology

Nerve signals for pattern vision

Supervisor: Dr Samuel Solomon, Physiology

 

Cancer, cell biology & embryo development

ES cells and neurogenesis

                  Supervisor: Dr Michael Morris, Physiology

Cell signaling in the preimplantation embryo

                  Supervisor: Dr Margot Day, Physiology

Development of Novel Tumour Agents for the Treatment of Cancer

Supervisor: Prof. Des Richardson, Pathology

The impact of pathogens on respiratory epithelium

Supervisor: Dr Anuwat Dinudom, Physiology

Brain Development

Supervisor: Dr Cathy Leamey

 

Infection, immunity & inflammation

Supervisor: Prof. Nick Hunt, Pathology

Lab projects

1: Expression of a newly-discovered enzyme in human tissues.

2: Expression and characterisation of a novel human enzyme.

3: Expression of indoleamine dioxygenase in response to Toll-like receptors in cell lines.

4: Expression and characterisation of a novel human enzyme.

5: Does modulation of the immune system determine the outcome of cerebral malaria?

Library Project: “Critically review the published literature on natural and artificial antioxidants as modifying agents in experimental rodent models of stroke.”

 

Chemokines involved in idiopathic inflammatory bowel disease (IBD)

Supervisor: Dr Bob Bao, Pathology

 

Further information                                                                                                                                                                                                                                                         

Further information on the Faculty of Science TSP can be found at http://www.science.usyd.edu.au/fstudent/undergrad/tsp/index.shtml

 

Other opportunities to gain research experience in Medical Science

Summer Research Scholarships

Summer Research Scholarships are available from the Faculty of Medicine for a period of eight weeks over the summer vacation. They offer a unique opportunity for students to obtain experience in medical-related research. The scholarships offer students the experience of working with well-established researchers in high quality medical research facilities.

For more infomation and a list of projects available go to http://www.medfac.usyd.edu.au/research/srs/index.php