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Selected Publications

Moran-Jones K, Ledger A and Naylor MJ. β1 integrin deletion enhances progression of prostate cancer in the TRAMP mouse model. Sci Rep. 2012;2:526.

Rogers RL, Van Seuningen I, Gould J, Hertzog PJ, Naylor MJ and Pritchard MA. Transcript Profiling of Elf5+/- Mammary Glands During Pregnancy Identifies Novel Targets of Elf5. PLOS One 2010; 5(10):e13150

Akhtar N, Marlow R, Lambert E, Lowe E, Cheung J, Katz E, Li W, Wu C, Dedhar S, Naylor MJ and Streuli CH. Molecular dissection of integrin signalling proteins in the control of mammary epithelial development and differentiation. Development 2009; 136: 1019-1027

Oakes SR*, Naylor MJ*, Asselin-Labat ML, Blazek KD, Gardiner-Garden M, Hilton HN, Kazlauskas M, Pritchard MA, Chodosh LA, Pfeffer PL, Lindeman GJ, Visvader JE and Ormandy CJ. The Ets transcription factor Elf5 is essential for specifying mammary alveolar cell fate. Genes Dev 2008; 22: 581-586. *Co-first authors

Harris J, Stanford P, Sutherland K, Oakes SR, Naylor MJ, Robertson FG, Blazek K, Kazlauskas M, Wittlin S, Alexander WS, Linderman GJ, Visvader JE and Ormandy CJ. Socs2 and Elf5 are key members of the set of prolactin-regulated genes that drive mammary gland development. Mol Endocrinol 2006; 20:1177-87.

Naylor MJ, Li N, Cheung J, Lowe EA, Lambert E, Wang P, Marlow R, Schatzmann F, Wintermantel T, Schuetz G, Clarke AR, Mueller U, Hynes NE and Streuli CH. Ablation of β1 integrins in mammary epithelium reveals a critical role for integrin in glandular morphogenesis and differentiation. J Cell Biol 2005; 171:717-28

Li N, Zhang Y, Naylor MJ, Schatzmann F, Maurer F, Wintermantel T, Schuetz G, Mueller U, Streuli CH and Hynes NE. β1 integrins regulate mammary gland proliferation and maintain the integrity of mammary luminal alveoli. EMBO J 2005; 24:1942-53.

Naylor MJ, Oakes SR, Gardiner-Garden M, Harris J, Blazek K, Ho TWC, Li FC, Wynick D, Walker AM and Ormandy CJ. Investigation of the transcriptional changes underlying the secretory activation phase of mammary gland development. Mol Endocrinol 2005; 19:1868-83.

Zhou J, Chehab R, Tkalcevic J, Naylor MJ, Harris J, Wilson TJ, Tsao S, Tellis I, Zavarsek S, Xu D, Lapinskas EJ, Visvader J, Lindeman GJ, Thomas R, Ormandy CJ, Hertzog PJ, Kola I, and Pritchard MA. Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation. EMBO J 2005; 24: 635-44.

Naylor MJ, Ginsburg E, Iismaa, TP, Vonderhaar BK, Wynick D and Ormandy CJ. The neuropeptide galanin augments lobuloalveolar development. J Biol Chem 2003; 278: 29145-29152.

Naylor MJ and Ormandy CJ. Mouse strain-specific patterns of mammary ductal side branching are elicited by stromal components. Dev Dynamics 2002; 225: 100-105

Lindeman GJ, Wittlin S, Lada H, Naylor MJ, Santamaria M, Zhang, JG, Starr R, Hilton DJ, Alexander WS, Ormandy CJ and Visvader J. SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice. Genes Dev 2001; 15: 1631-1636.

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